PVCs, VT, atrial fibrillation, flutter, PAT-
Child: 40-60 mg/kg PO qd in 4-6 divided doses or 1.5 gram/m2 PO qd in 4-6 divided doses. Or 2-5 mg/kg IV (max 100 mg) q 10-30 min prn.Max 30 mg/kg in 24 h.
Adult: 50-100 mg q 5 min slow IV push, max 25-50 mg/min, until arrhythmias disappear, adverse effects develop, or 500 mg given. Then continue infusion of 1-6 mg/min. If arrhythmias recur, repeat bolus and increase infusion rate. Or 50 mg/kg IM divided q 3-6 h; perioperative: 100-500 mg IM. Or 50 mg/kg PO in divided doses q 3 h. Once pt stable, may give sustained-release form q 6 h or extended-release form at 50 mg/kg in 2 divided doses q 12 h.
Prevention atrial fibrillation or PAT-
Adult: 1-1.25 gram PO. If arrhythmias persist after 1 h, give 750 mg. If no change, give 500 mg-1 gram q 2 h until arrhythmias disappear or adverse effects occur.
Prevention VT-
Adult: 1 gram PO. Maintenance: 50 mg/kg/day q 3 h; avg 250-500 mg q 4 h but may need 1-1.5 gram q 4-6 h. |